Bi-Est (Estriol + Estradiol)Rx

Daily oral capsule

Starting at $80/month

Bi-Est combines estriol and estradiol in a single bioidentical preparation, prescribed for hot flashes, night sweats, sleep disruption, mood changes, and vaginal dryness in peri-menopause and menopause.

Prescription products require a medical evaluation. A licensed provider will review your intake before any medication is dispensed. Availability varies by state.

Choose your form

Topical cream · 80/2030g · 1mg/mLfrom $80/month Topical cream · 50/5030g · 1mg/mLfrom $80/month Sustained-release capsule · 80/2030 SR Capsules · 0.5mgfrom $71/month Sustained-release capsule · 50/5030 SR Capsules · 0.5mgfrom $71/month Troche · 80/2030 Troches · 1mgfrom $80/month Rapid-dissolve sublingual · 80/2030 Sublingual Rapid Dissolve Tablets · 1mgfrom $80/month

Choose your strength

Most people start at the lowest strength. You can step up later, and the price follows the strength you choose.

1mgStarter$80/month 2.5mg$80/month 5mg$80/month 10mg$80/month

Your provider confirms the form, strength, and dose that fit your history during your consultation.

1 Month, $893 Months, $240 ($80/Month)

Try Bi-Est (Estriol + Estradiol) today See how it works

Hot Flashes & Night Sweats
Sleep & Mood
Vaginal Comfort

Prescription products require a medical evaluation. A licensed provider will review your intake before any medication is dispensed. Availability varies by state.

LegitScript certified

Independently reviewed against strict telehealth and pharmacy standards.

U.S. pharmacy partners

Prescriptions are filled by Licensed U.S. 503A FDA Regulated Pharmacies.

Licensed in all 50 states

Our clinicians are licensed where you live and review every plan personally.

Private & HIPAA-aware

Your health information is handled under our privacy and telehealth policies.

Prescription products marked Rx require a medical evaluation and are prescribed only when a licensed provider determines treatment is appropriate. Compounded medications are not FDA-approved products. Important safety information.

How it works

Choose a topical cream, a sustained-release capsule, a troche, or a rapid-dissolve sublingual tablet, in either a 50/50 or 80/20 estriol-to-estradiol ratio. Your provider selects the ratio, form, and dose from your symptoms and labs.

Questions about Bi-Est (Estriol + Estradiol) — Rapid-dissolve sublingual · 80/20 — 5mg? We’ve got answers.

See more in our Help Center

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Hormone (HRT)

Bi-Est (Estriol + Estradiol) — Rapid-dissolve sublingual · 80/20 — 5mg

$80/month

Hot Flashes & Night Sweats
Sleep & Mood
Vaginal Comfort

Get started

Prescription only after a licensed provider determines treatment is appropriate.